Overview
Octet systems enable real-time, label-free analysis for determination of affinity, kinetics, and antibody/protein quantitation. Based on Bio-Layer Interferometry (BLI), this fluidics-free instrument platform offers a number of advantages over traditional label-free techniques including operation in a 384-well format.
Description
Octet RED384 Biolayer Interferometry (BLI) Label-Free Detection System for Biomolecular Interaction Analysis
The 16-Channel High-Throughput Octet RED384 Instrument
The Octet RED384 system offers label-free molecular interaction analysis with state-of-the-art high throughput platforms that facilitate the rapid characterization and development of synthetic molecules.
The high detection sensitivity and throughput of the Octet RED384 system have also made it a favorite for small molecule library screening and analysis of large cross-competition binding matrices. Target ligands can be batch immobilized onto biosensors and returned to the biosensor tray for re-use in future experiments, thus extending the number of uses for each biosensor, preserving valuable ligand, and maximizing flexibility in experimental design.
Applications
Characterization of the binding affinity and kinetics of purified glycans or glycoproteins with receptor proteins or other glycans. Quantitation of IC50 and Ki values relevant to inhibitor design and development.
Associated Equipment: 8-channel Octet RED96 system
Instrument Status: Available
User Access: The Octet RED384 Instrument is a GlycoMIP-supported resource; freely available to approved users of the GlycoMIP user facility.
For access to this equipment and other GlycoMIP services, please visit the User Portal.
